Butaret Syrup 100ml

Composition

Butamirate Citrate

Uses of Butaret Syrup

• Cough (non-productive)
• Whooping cough
• Pre-post operative cough
• Cough suppression

Side Effects of Butaret Syrup

Overall, the tolerance of Butamirate Citrate is good. Rare adverse reactions such as rash, nausea, diarrhea, and vertigo have been observed, resolving after dose reduction or treatment withdrawal.

How does Butaret Syrup work?

Butamirate acts centrally as a cough suppressant, effectively targeting non-productive cough.

Quick Suggestions:

• Butamirate is effective for treating non-productive (dry) cough by suppressing the cough reflex.
• It works centrally in the brain to suppress cough and is not chemically or pharmacologically related to opium alkaloids.
• Besides its antitussive effect, Butamirate also helps reduce airway resistance, making breathing easier.
• After oral intake, Butamirate is rapidly and completely absorbed by the body.
• With sustained-release tablets, the maximum concentration of Butamirate in the body is typically reached within 9 hours.
• Butamirate is highly protein-bound, ensuring its efficacy and duration of action.
• It has a relatively long plasma elimination half-life of about 13 hours, providing sustained relief from cough.
• Butamirate is indicated for acute cough of any cause, as well as for pre-and post-operative cough sedation during surgical procedures and bronchoscopy.

Pharmacology of Butaret 100 ml Syrup:

Butamirate Citrate acts directly on the brain's cough center to suppress cough. It is safe and non-sedating, neither chemically nor pharmacologically related to opium alkaloids. After oral administration, Butamirate Citrate is rapidly and completely absorbed. The maximum concentration is reached within 9 hours with the sustained-release tablet. It is highly protein-bound and has a plasma elimination half-life of approximately 13 hours. The active metabolites of Butamirate Citrate also exhibit antitussive activity.

Administration & Dosage of Butaret 100 ml Syrup:

• Use in adults:
  • Butamirate Citrate 50 mg tablet: Take 2-3 tablets daily.
  • Butamirate Citrate syrup: Take 15 ml 4 times daily.
• Use in children & adolescents:
  • Butamirate Citrate 50 mg tablet:
    • Adolescents over 12 years old: Take 1-2 tablets daily.
  • Butamirate Citrate syrup:
    • Children (3-6 yrs): Take 5 ml 3 times daily.
    • Children (6-12 yrs): Take 10 ml 3 times daily.
    • Adolescent: Take 15 ml 3 times daily.
  • Butamirate Citrate pediatric drops:
    • Children (2 months - 1 yr): Take 0.50 ml 4 times daily.
    • Children (1-3 yrs): Take 0.75 ml 4 times daily.

Interaction

Concomitant use of expectorants may lead to mucous retention in the respiratory system, increasing the risk of bronchospasm and airway infection.

Contraindications

Hypersensitivity to the medication.

Pregnancy & Lactation

Butamirate Citrate should be avoided during the first trimester of pregnancy. During the remainder of pregnancy, it can be used if indicated by a physician but with caution. Caution should also be exercised during breastfeeding due to insufficient data on its elimination in breast milk.

Precautions & Warnings

Butamirate Citrate suppresses the cough reflex; therefore, concurrent use with expectorants should be avoided to prevent mucus retention and reduce the risk of bronchospasm and respiratory infections. If a cough persists for more than 7 days (more than 3 days in children under 12 years of age), medical advice should be sought.

Storage Conditions:

Store below 30°C, protected from light and moisture. Keep out of children's reach.